Upfront Modified Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan Plus Panitumumab Versus Fluorouracil, Leucovorin, and Oxaliplatin Plus Panitumumab for Patients With RAS/BRAF Wild-Type Metastatic Colorectal Cancer: The Phase III TRIPLETE Study by GONO
Author(s): Daniele Rossini, MD1,2;Carlotta Antoniotti, MD, PhD1,2;Sara Lonardi, MD3;Filippo Pietrantonio, MD4;Roberto Moretto, MD2;Lorenzo Antonuzzo, MD, PhD5;Alessandra Boccaccino, MD1,2;Federica Morano, MD4;Marco Brugia, MD6;Carmelo Pozzo, MD7;Federica Marmorino, MD, PhD1,2;Francesca Bergamo, MD8;Emiliano Tamburini, MD9;Alessandro Passardi, MD10;Giovanni Randon, MD4;Sabina Murgioni, MD8;Beatrice Borelli, MD1,2;Angela Buonadonna, MD11;Mirella Giordano, PhD1,2;Gabriella Fontanini, MD, PhD12;Veronica Conca, MD1,2;Vincenzo Formica, MD, PhD13;Massimo Aglietta, MD14;Roberto Bordonaro, MD15;Giuseppe Aprile, MD16;Gianluca Masi, MD1,2;Luca Boni, MD17;and Chiara Cremolini, MD, PhD1,2
Author Affiliations
1Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy2Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy3Medical Oncology 3, Veneto Institute of Oncology IOV—IRCCS, Padua, Italy4Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy5Clinical Oncology Unit, Careggi University Hospital—Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy6Medical Oncology Unit, Careggi University Hospital, Florence, Italy7Medical Oncology, Comprehensive Cancer Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy8Medical Oncology 1, Veneto Institute of Oncology IOV—IRCCS, Padua, Italy9Oncology and Palliative Care Department, Cardinale G. Panico Tricase City Hospital, Tricase, Italy10Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori,” Meldola, Italy11Department of Medical Oncology, CRO Aviano, National Cancer Institute, IRCCS, Aviano, Italy12Department of Surgical, Medical, Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy13Medical Oncology Unit, Tor Vergata University Hospital, Rome, Italy14Medical Oncology, Candiolo Cancer Institute, Fondazione del Piemonte per l’Oncologia (FPO)-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Torino, Italy15Medical Oncology Unit, Azienda Ospedaliera di Rilievo Nazionale e Alta Specializzazione (ARNAS), Ospedale Garibaldi, Catania, Italy16Department of Oncology, San Bortolo General Hospital, Azienda ULSS8 Berica, Vicenza, Italy17Clinical Epidemiology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy